GNE-0011

SKU: orb3032978

Description

GNE-0011 is a monovalent, JQ1-based BRD4 degrader that is not linked to an E3 ligase binder, triggers proteasomal and ubiquitin-dependent selective degradation of BRD4 over BRD2 and BRD3.

Key Properties

• CAS Number: 2413382-30-4
• MW: 475.61
• Purity: 0.98
• Formula: C₂₆H₂₉N₅O₂S
• SMILES: C12SC(C)=C(C)C=1C(C1=CC=C(C#CCN)C=C1)=N[C@@H](CC(=O)OC(C)(C)C)C1=NN=C(C)N12

Storage & Handling

• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only