Glycitein

SKU: orb1222280

Description

Glycitein is found in soy and red clover. It exhibits a variety of biological activities, including increasing Nrf2-related antioxidative signaling, preventing invasion in glioma cells destabilizing amyloid-β aggregates and preventing fibril assembly, and inhibiting osteoclast generation.

Key Properties

• CAS Number: 40957-83-3
• MW: 284.26
• Purity: >98% (HPLC)
• Formula: C₁₆H₁₂O₅
• SMILES: COC1=C(C=C2C(=C1)C(=O)C(=CO2)C3=CC=C(C=C3)O)O
• Target: P2 Receptor
• Solubility: In Vitro: DMSO : 25 mg/mL (87.95 mM)

Bioactivity

• In Vitro:
  Cell Viability Assay Cell line: human gastric cancer cells (AGS, MKN-28, MKN-45, NCI-N87, YCC-1, YCC-6, SNU-5, SNU-216, SNU-484, SNU-668). Concentration: 24 h. Incubation time: 0-100 μM. Result: IC50: 30.98, 60.17, 35.07, 36.05, 33.11, 88.62, 97.68, 83.02, 46.87, 87.55 μM respectively. Apoptosis Analysis Cell line: AGS cells. Concentration: 30 μM. Incubation time: 3, 6, 12, and 24 hr. Result: Increased the expression of Bax, Caspase-3 and cleaved PARP protein, and decreased levels of Bcl-2.

Storage & Handling

• Storage: Storage temperature: -20°C. Stability: ≥ 2 years
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Glycitein | Q-100465

Quick Database Links

Gene Symbol

P2 Receptor