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Glutaminase C-IN-3

SKU: orb3174160

Description

GlutaminaseC-IN-3 is a potent allosteric inhibitor of glutaminase C (GAC) with an EC50 of 116 nM. It modulates cellular metabolites and elevates reactive oxygen species (ROS) production by inhibiting glutamine metabolism. In A549 xenograft mouse models, GlutaminaseC-IN-3 demonstrates significant antitumor activity. This compound is applicable for research on non-small cell lung cancer (NSCLC).

Research Area

Immunology & Inflammation, Protein Biochemistry

Images & Validation

Key Properties

TargetGlutaminase,ROS

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Protocol Information