Glutamate-cysteine ligase inhibitor EN25

SKU: orb3033001

Description

EN25 is a covalent allosteric inhibitor of glutamate-cysteine ligase (GCL), selectively targeting cysteine residue C114 on the GCLM regulatory subunit with an IC50 of 16 μM.

Research Area

Neuroscience; Pharmacology & Drug Discovery; Molecular Biology

Key Properties

• CAS Number: 1647534-29-9
• MW: 416.535264968872
• Purity: >98%
• Formula: C₂₅H₂₄N₂O₂S
• SMILES: S(C1C=CC(=CC=1)NC(C1C=CC(=CC=1)CNC(C=C)=O)=O)C1C=CC(C)=C(C)C=1

Storage & Handling

• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only