GLUT1/EGFR-IN-1

SKU: orb2646232

Description

GLUT1/EGFR-IN-1 (compound H) is a dual inhibitor targeting the EGFR kinase ATP-binding site and GLUT1-mediated glucose metabolism. It reduces ATP, lactate, and nuclear EGFR, showing research utility in nasopharyngeal and triple-negative breast cancer models in vitro and in vivo.

Research Area

Cardiovascular Research, Cell Biology, Metabolism Research, Signal Transduction

Key Properties

• CAS Number: 2393787-80-7
• MW: 696.75
• Formula: C₄₄H₃₂N₄O₅
• SMILES: O=C(NC=1C=CC2=NC=NC(NC3=CC=C(C=C3)C)=C2C1)C4=CC(OCC=5C=CC=CC5)=C6C(=O)C=7C(OCC=8C=CC=CC8)=CC=CC7C(=O)C6=C4
• Target: Apoptosis,EGFR,transporter

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

171357841