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Glucocorticoid receptor/IL-6-IN-2

SKU: orb3173572

Description

Glucocorticoid receptor/IL-6-IN-2 (Compound 36) is a selective dual inhibitor of the glucocorticoid receptor (GR) and the IL-6 signaling pathway, with IC50 values of 120 nM and 59 nM, respectively. It shows potential for research in inflammatory diseases such as rheumatoid arthritis and asthma.

Research Area

Immunology & Inflammation, Metabolism Research

Images & Validation

Key Properties

CAS Number1198784-83-6
MW517.95
FormulaC22H23ClF3N3O4S
SMILESO=C(N)C1=CC(Cl)=CC=C1C(C)(C)CC(O)(CC2=CC=3C=C(N=CC3N2)S(=O)(=O)C)C(F)(F)F
TargetGlucocorticoid Receptor,Interleukin

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Protocol Information