GLP-1R modulator-1

SKU: orb3135051

Description

GLP-1R modulator-1 (Compound 384) is a potent and orally active selective agonist of the glucagon-like peptide-1 receptor (GLP-1R). It activates G protein-coupled signaling, leading to increased intracellular cAMP levels, enhanced insulin secretion, delayed gastric emptying, and reduced appetite. GLP-1R modulator-1 holds potential for research in type 2 diabetes, obesity, and non-alcoholic steatohepatitis (NASH).

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Key Properties

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CAS Number	2978244-71-0
MW	733.23
Formula	C₄₁H₃₈ClFN₆O₄
SMILES	C[C@]1(OC=2C(O1)=CC=CC2C=3CCN(CC=4N(C[C@@H]5CCO5)C=6C(N4)=CC(NC(=O)C=7C=C8C(=C(C)C7)NN=C8C)=CC6)CC3)C9=C(F)C=C(Cl)C=C9
Target	Glucagon Receptor

Storage & Handling

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Storage	-20°C
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

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Gene Symbol

Glucagon Receptor

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