Glipizide

SKU: orb1308053

Description

Glipizide (CP 28720) is a second-generation sulfonylurea used as a hypoglycemic agent in research. It is widely applied in studies of type 2 diabetes, facilitating investigations into insulin secretion mechanisms and metabolic regulation in both in vitro and in vivo experimental models.

Research Area

Metabolism Research, Molecular Biology, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 29094-61-9
• MW: 445.54
• Purity: 99.75% (May vary between batches)
• Formula: C₂₁H₂₇N₅O₄S
• SMILES: S(NC(NC1CCCCC1)=O)(=O)(=O)C2=CC=C(CCNC(=O)C=3C=NC(C)=CN3)C=C2
• Target: Potassium Channel,ABC Transporter,PPAR
• Solubility: Ethanol:< 1 mg/mL (insoluble or slightly soluble);10% DMSO+90% Corn Oil:3.3 mg/mL (7.41 mM);DMSO:82 mg/mL (184.05 mM)

Bioactivity

• Target IC50:
  KATP:6.4 nM ATP-sensitive potassium (IC50)

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

ATP-sensitive potassium, ABCC, CP28720, CP-28720, CP 28720, pancreatic β, KcsA, inhibit, K 4024, K ATP, K4024, K-4024, Glipizide, Inhibitor, mellitus, PotassiumChannel, Potassium Channel, PPARγ, sulfonylurea class, type 2 diabetes

Compound Identifiers

PubChem CID

3478