Gliclazide

SKU: orb1308313

Description

Gliclazide (SE1702) is a sulfonylurea insulin secretagogue that promotes insulin secretion from pancreatic beta-cells. It is widely used in diabetes research, including in vitro studies of insulin release mechanisms and in vivo models of type 2 diabetes.

Research Area

Pharmacology & Drug Discovery

Key Properties

• CAS Number: 21187-98-4
• MW: 323.41
• Purity: 98.08% (May vary between batches)
• Formula: C₁₅H₂₁N₃O₃S
• SMILES: CC1=CC=C(C=C1)S(=O)(=O)NC(=O)NN1CC2CCCC2C1
• Target: Potassium Channel
• Solubility: H2O:< 1 mg/mL (insoluble or slightly soluble);10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (6.18 mM);Ethanol:< 1 mg/mL (insoluble or slightly soluble);DMSO:45 mg/mL (139.14 mM)

Bioactivity

• Target IC50:
  K+ channel:184 nM

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Gliclazide, KcsA, Inhibitor, inhibit, SE1702, SE-1702, SE 1702, PotassiumChannel, Potassium Channel, S 1702, S1702, S-1702

Compound Identifiers

PubChem CID

3475