GLI1-IN-1

SKU: orb2566183

Description

GLI1-IN-1 (CBC-1) is a water-soluble small molecule inhibitor of the Hedgehog pathway component GLI1 (IC50 = 1.3 μM). It demonstrates anticancer activity by inducing apoptosis and suppressing tumor growth in colorectal cancer models, supporting its use in both in vitro and in vivo oncological research.

Research Area

Cell Biology, Pharmacology & Drug Discovery, Stem Cell & Developmental Biology

Key Properties

• CAS Number: 2923907-92-8
• MW: 736.93
• Formula: C₄₂H₆₀N₂O₉
• SMILES: C[C@@]12[C@@](O)([C@@]3(O)[C@](C[C@H]1OC(/C=C/C4=CC=CC=C4)=O)([C@]5(C)C(=CC3)C[C@@H](OC(CN6CCN(C)CC6)=O)CC5)[H])CC[C@]2([C@@H](OC([C@H](CC)C)=O)C)O
• Target: Hedgehog/Smoothened,Apoptosis

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

172653063