Glesatinib hydrochloride

SKU: orb1707270

Description

Glesatinib hydrochloride is an orally bioavailable, dual MET/SMO tyrosine kinase inhibitor. It has demonstrated activity in preclinical models of non-small cell lung cancer (NSCLC), including overcoming P-glycoprotein-mediated multidrug resistance in both in vitro and in vivo studies.

Research Area

Signal Transduction

Key Properties

• CAS Number: 1123838-51-6
• MW: 656.16
• Formula: C₃₁H₂₈ClF₂N₅O₃S₂
• SMILES: Cl.COCCNCc1ccc(nc1)-c1cc2nccc(Oc3ccc(NC(=S)NC(=O)Cc4ccc(F)cc4)cc3F)c2s1
• Target: c-Met/HGFR,TAM Receptor

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

127255607