GK420

SKU: orb2945736

Description

GK420 (AVX420) is a potent and selective cPLA2α inhibitor with an XI(50) of 0.0016, effectively blocking arachidonic acid release (EC50 = 0.09 µM). This tool compound is widely used in cancer research to investigate lipid signaling pathways in both cellular and animal models of inflammation and oncology.

Research Area

Metabolism Research

Key Properties

• CAS Number: 1621517-60-9
• MW: 391.481
• Formula: C₂₀H₂₅NO₅S
• SMILES: O=C(OC)C=1N=C(SC1)C(=O)COC2=CC=C(OCCCCCCC)C=C2
• Target: Phospholipase

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

77847540