Ginsenoside Rd

SKU: orb1304899

Description

Ginsenoside Rd (Gypenoside VIII) is a bioactive saponin studied for its potential antitumor properties. Research indicates it may inhibit tumor cell proliferation in vitro and suppress tumor growth in vivo, making it a compound of interest for oncology and pharmacology research.

Research Area

Immunology & Inflammation, Metabolism Research, Neuroscience, Pharmacology & Drug Discovery, Signal Transduction

Key Properties

• CAS Number: 52705-93-8
• MW: 947.15
• Purity: 99.13% (May vary between batches)
• Formula: C₄₈H₈₂O₁₈
• SMILES: [H][C@@]12[C@H](CC[C@@]1(C)[C@]1(C)CC[C@@]3([H])C(C)(C)[C@H](CC[C@]3(C)[C@@]1([H])C[C@H]2O)O[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O)C(C)(CCC=C(C)C)O[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O
• Target: Calcium Channel,COX,Endogenous Metabolite,NF-κB,Cytochromes P450
• Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (2.11 mM);DMSO:50 mg/mL (52.79 mM)

Bioactivity

• Target IC50:
  NF-κB:12.05 μM (in HepG2 cells)|CYP3A4:81.7±2.6 μM|CYP2C9:85.1±9.1 μM|CYP1A2:78.4±5.3 μM|CYP2D6:58.0±4.5 μM

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

P450, Sanchinoside Rd, Inhibitor, Gypenoside VIII, Ginsenoside Rd, EndogenousMetabolite, Endogenous Metabolite, inhibit, Nuclear factor-kappaB, Nuclear factor-κB, NF-kB, NFκB, NF-κB, NFkB, Panaxoside Rd, COX, CalciumChannel, Cytochrome P450, CYPs, Cyclooxygenase, Calcium Channel, Ca channels, Ca2+ channels

Compound Identifiers

PubChem CID

129010066