Ginsenoside C-K hexapropionate ester

SKU: orb3175038

Description

Ginsenoside C-K hexapropionate ester (Structure 2) acts as a selective agonist for LXRα without significantly activating LXRβ. By stimulating LXRα, it enhances the expression of downstream genes such as ABCA1, facilitating reverse cholesterol transport and reducing lipid accumulation in macrophage-derived foam cells, making it useful for atherosclerosis research. This compound is a synthetic derivative, created by modifying the active metabolite of Panax notoginseng saponins, Ginsenoside Compound K, with propionic anhydride.

Key Properties

• CAS Number: 2861254-89-7
• MW: 959.27
• Formula: C₅₄H₈₆O₁₄
• SMILES: C[C@]12[C@@]([C@@]([C@@](O[C@H]3[C@H](OC(CC)=O)[C@@H](OC(CC)=O)[C@H](OC(CC)=O)[C@@H](COC(CC)=O)O3)(CCC=C(C)C)C)(CC1)[H])([C@H](OC(CC)=O)C[C@]4([C@@]2(C)CC[C@@]5([C@]4(C)CC[C@H](OC(CC)=O)C5(C)C)[H])[H])[H]
• Target: Liver X Receptor

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

Liver X Receptor