Ghrelin receptor full agonist-3

SKU: orb3174091

Description

Ghrelin receptor full agonist-3 (Compound 22) is a selective, potent, orally active full agonist of the growth hormone secretagogue receptor (ghrelin receptor) with an EC50 value of 1.8 nM. It stimulates pulsatile secretion of growth hormone (GH), significantly increasing both the frequency and duration of GH release, thereby inducing a sustained rise in insulin-like growth factor-1 (IGF-1) levels. This compound is applicable for research in oncology and chronic obstructive pulmonary disease.

Research Area

Metabolism Research, Pharmacology & Drug Discovery, Signal Transduction

Key Properties

• CAS Number: 2243167-93-1
• MW: 518.07
• Formula: C₂₅H₃₂ClN₅O₃S
• SMILES: CC1(C)[C@@]2(C[C@H](C(N[C@H]3CCCNC3)=O)[C@@H](NC(=O)C=4SC(=NN4)C5=C(Cl)C=CC=C5)C2)OCC1
• Target: GHSR,IGF-1R,GHR

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

GHSR,IGF-1R,GHR