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GHN105

SKU: orb2944427

Description

GHN105 is an orally bioavailable small molecule STING inhibitor with an IC50 of 4.4 μM in THP-1 cells. It reduces pro-inflammatory cytokines in vivo and alleviates symptoms in a DSS-induced colitis mouse model, supporting its use in researching STING-driven inflammatory and autoimmune diseases.

Research Area

Immunology & Inflammation

Images & Validation

Key Properties

MW800.89
FormulaC41H56N2O14
TargetInterleukin,STING,IFNAR

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Protocol Information

GHN105 (orb2944427)

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Step 1: Enter information below

(Recommended: An additional animal making an allowance for loss during the experiment)

Step 2: Enter the in vivo formulation

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