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GGTI-286 hydrochloride

SKU: orb1687062

Description

GGTI-286 hydrochloride is a potent inhibitor of GGTase I (IC50: 2 µM) and effectively blocks K-Ras4B farnesylation (IC50: 1 µM). This compound is a valuable research tool for studying Ras-dependent signaling pathways and has been utilized in both in vitro and in vivo cancer research models.

Research Area

Pharmacology & Drug Discovery, Signal Transduction

Images & Validation

Key Properties

CAS Number181141-66-2
MW466.04
FormulaC23H32ClN3O3S
SMILESCl.COC(=O)[C@H](CC(C)C)NC(=O)c1ccc(NC[C@@H](N)CS)cc1-c1ccccc1
TargetOthers,Ras

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Key Properties

No computed properties available.

Protocol Information