GGFG-PAB-MMAE

SKU: orb2695419

Description

GGFG-PAB-MMAE (Comp 58054-1) is an antibody-drug conjugate (ADC) linker-payload featuring the protease-cleavable valine-citrulline linker GGFG-PAB conjugated to the cytotoxic agent MMAE, a potent tubulin inhibitor. This conjugate is widely used in ADC research for targeted cancer therapy development, enabling the study of drug delivery and efficacy in both in vitro and in vivo models.

Research Area

Signal Transduction

Key Properties

• CAS Number: 3049886-19-0
• MW: 1185.45
• Formula: C₆₂H₉₂N₁₀O₁₃
• SMILES: [C@H]([C@H](C(N[C@@H]([C@@H](O)C1=CC=CC=C1)C)=O)C)(OC)[C@]2(N(C(C[C@H]([C@@H](N(C([C@@H](NC([C@@H](N(C(OCC3=CC=C(NC(CNC([C@H](CC4=CC=CC=C4)NC(CNC(CN)=O)=O)=O)=O)C=C3)=O)C)[C@@H](C)C)=O)C(C)C)=O)C)[C@H](CC)C)OC)=O)CCC2)[H]
• Target: Drug-Linker Conjugates for ADC,Microtubule Associated

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

172652644