GGFG-amide-glycol-amide-Exatecan

SKU: orb2279053

Description

Exatecan (Intermediate 2) is a key synthetic derivative used to construct antibody-drug conjugates (ADCs) for targeted cancer therapy research. This compound enables the linkage of the potent topoisomerase I inhibitor exatecan to antibodies, facilitating the study of ADC efficacy in both in vitro and in vivo models.

Research Area

Molecular Biology

Key Properties

• CAS Number: 2866301-18-8
• MW: 870.88
• Formula: C₄₃H₄₇FN₈O₁₁
• SMILES: N(C(OCCOCNC(CNC([C@H](CC1=CC=CC=C1)NC(CNC(CN)=O)=O)=O)=O)=O)[C@@H]2C3=C4C(C=5N(C4)C(=O)C6=C(C5)[C@](CC)(O)C(=O)OC6)=NC=7C3=C(CC2)C(C)=C(F)C7
• Target: Drug-Linker Conjugates for ADC,Topoisomerase

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

171361076