Genkwadaphnin

SKU: orb1942440

Description

Genkwadaphnin is a daphnane diterpenoid that acts as an importin-β1 inhibitor, thereby blocking the nuclear translocation of key drivers in castration-resistant prostate cancer (CRPC). This mechanism suppresses oncogenic signaling, demonstrating potent anti-tumor activity in both in vitro studies and in vivo mouse models of CRPC.

Key Properties

• CAS Number: 55073-32-0
• MW: 602.63
• Formula: C₃₄H₃₄O₁₀
• SMILES: C[C@H]1[C@]23[C@]([C@@]4([C@](C(C)=C)([C@@H]1OC(=O)C5=CC=CC=C5)O[C@](O2)(O4)C6=CC=CC=C6)[H])([C@]7([C@](CO)(O7)[C@@H](O)[C@@]8(O)[C@]3(C=C(C)C8=O)[H])[H])[H]

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

73351913