GEM–IB

SKU: orb1942439

Description

The GEM-IB conjugate, linking gemcitabine-5'-phosphate to ibandronate, demonstrates single-agent and docetaxel-synergistic activity in osteosarcoma research. It reduces tumor growth, preserves bone integrity, and improves survival in murine models, supporting its study in bone-targeted oncology and preclinical therapeutic experiments.

Key Properties

• CAS Number: 2866211-93-8
• MW: 644.39
• Formula: C₁₈H₃₃F₂N₄O₁₃P₃
• SMILES: FC1(F)[C@@H](O[C@H](COP(OP(C(CCN(CCCCC)C)(P(=O)(O)O)O)(=O)O)(=O)O)[C@H]1O)N2C(=O)N=C(N)C=C2
• Target: Others

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

163196442