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Gemcitabine elaidate

SKU: orb1707274

Description

Gemcitabine elaidate (CP-4126) is a lipophilic prodrug of gemcitabine designed for improved cellular uptake. Upon intracellular activation, it generates metabolites that inhibit DNA synthesis and cause chain termination, leading to apoptosis. This compound has been investigated in preclinical in vitro and in vivo studies for its potential antineoplastic activity against various cancers.

Research Area

Cell Biology, Molecular Biology

Images & Validation

Key Properties

CAS Number210829-30-4
MW527.64
FormulaC27H43F2N3O5
SMILESCCCCCCCC\C=C\CCCCCCCC(=O)OC[C@H]1O[C@@H](n2ccc(N)nc2=O)C(F)(F)[C@@H]1O
TargetAutophagy,Apoptosis,Nucleoside Antimetabolite/Analog

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Key Properties

No computed properties available.

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Gemcitabine elaidate (orb1707274)

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(Recommended: An additional animal making an allowance for loss during the experiment)

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