Geiparvarin

SKU: orb3141909

Description

Geiparvarin is an anticancer agent that acts as an inhibitor of MAO-B (pIC50= 6.84 μM). It exerts its antitumor effects by downregulating COX2 expression and inhibiting angiogenesis. Geiparvarin halts the cell cycle at the G1 phase and induces apoptosis in cancer cells. Additionally, it exhibits antimicrotubule activity (Microtubule/Tubulin) and disrupts the cytoskeleton, contributing to its antiproliferative properties. Geiparvarin is of research interest for its potential effects on lung cancer, leukemia, and breast cancer.

Research Area

Cell Biology, Immunology & Inflammation, Neuroscience, Protein Biochemistry, Signal Transduction

Key Properties

• CAS Number: 36413-91-9
• MW: 326.34
• Formula: C₁₉H₁₈O₅
• SMILES: O(C/C=C(\C)/C=1OC(C)(C)C(=O)C1)C=2C=C3C(=CC2)C=CC(=O)O3
• Target: Caspase,Monoamine Oxidase,Microtubule Associated,Apoptosis,COX

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

Caspase,Monoamine Oxidase,Microtubule Associated,Apoptosis,COX