Gefitinib N-oxide

SKU: orb1709621

Description

Gefitinib is a potent and selective EGFR tyrosine kinase inhibitor, with an IC50 range of 2-37 nM. Its N-oxide derivative is a key metabolite studied in cancer research, utilized in both in vitro cell-based assays and in vivo models to investigate EGFR-driven oncogenesis and drug metabolism.

Research Area

Cardiovascular Research, Signal Transduction

Key Properties

• CAS Number: 847949-51-3
• MW: 462.9
• Formula: C₂₂H₂₄ClFN₄O₄
• SMILES: N(C=1C2=C(C=C(OC)C(OCCCN3(=O)CCOCC3)=C2)N=CN1)C4=CC(Cl)=C(F)C=C4
• Target: Others,EGFR

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

123134766