Gefitinib dihydrochloride

SKU: orb1686410

Description

Gefitinib dihydrochloride is an orally bioavailable, selective EGFR tyrosine kinase inhibitor (IC50: 33 nM). It effectively blocks EGFR autophosphorylation and tumor cell growth, inducing autophagy and apoptosis. This compound is widely used in cancer research, including in vitro and in vivo studies for non-small cell lung cancer and breast cancer.

Research Area

Cardiovascular Research, Cell Biology, Signal Transduction

Images & Validation

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Key Properties

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CAS Number	184475-56-7
MW	519.82
Formula	C₂₂H₂₆Cl₃FN₄O₃
SMILES	Cl.Cl.COc1cc2ncnc(Nc3ccc(F)c(Cl)c3)c2cc1OCCCN1CCOCC1
Target	Autophagy,Others,EGFR,Apoptosis

Storage & Handling

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Storage	-20°C
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

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Compound Identifiers

PubChem CID

19077503 ↗

Key Properties

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No computed properties available.

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