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Catalog Number | orb1685655 |
---|---|
Category | Small Molecules |
Description | GDC-0349 |
CAS Number | 1207360-89-1 |
Purity | 98.98% |
MW | 452.55 |
SMILES | C[C@@H]1N(C2=C3C(=NC(=N2)C4=CC=C(NC(NCC)=O)C=C4)CN(CC3)C5COC5)CCOC1 |
Formula | C24H32N6O3 |
Biological Activity | GDC-0349 (RG-7603) is a potent and selective ATP-competitive inhibitor of mTOR with Ki of 3.8 nM, 790-fold inhibitory effect against PI3Kα and other 266 kinases. Phase 1. |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
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