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GCN2iB acetate

SKU: orb1739651

Description

GCN2iB is a selective GCN2 kinase inhibitor used in cancer research. It sensitizes ASNS-low cancer cells to L-asparaginase treatment, as demonstrated in both in vitro and in vivo studies, highlighting its potential application in investigating combination therapies for leukemia and other malignancies.

Research Area

Metabolism Research

Images & Validation

Key Properties

CAS Number2183470-13-3
MW511.8848
FormulaC20H16ClF2N5O5S
SMILESCC(O)=O.COc1ncc(Cl)cc1S(=O)(=O)Nc1ccc(F)c(C#Cc2cnc(N)nc2)c1F
TargetOthers,Endogenous Metabolite

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Key Properties

No computed properties available.

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GCN2iB acetate (orb1739651)

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(Recommended: An additional animal making an allowance for loss during the experiment)

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