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GCN2iB acetate
Catalog Number: orb1739651
| Catalog Number | orb1739651 |
|---|---|
| Category | Small Molecules |
| Description | GCN2iB acetate |
| CAS Number | 2183470-13-3 |
| Purity | 0.98 |
| MW | 511.8848 |
| SMILES | CC(O)=O.COc1ncc(Cl)cc1S(=O)(=O)Nc1ccc(F)c(C#Cc2cnc(N)nc2)c1F |
| Formula | C20H16ClF2N5O5S |
| Biological Activity | GCN2iB is a GCN2 inhibitor. GCN2iB may be useful for the treatment of cancer. The inhibition of GCN2 sensitizes cancer cells with low basal-level expression of asparagine synthetase (ASNS) to the antileukemic agent L-asparaginase (ASNase) in vitro and in vivo. |
| Storage | -20°C |
| Note | For research use only |
| Expiration Date | 12 months from date of receipt. |
