GB1874

SKU: orb1737856

Description

GB1874 is a small molecule inhibitor that disrupts the β-catenin/TCF4 interaction within the Wnt signaling pathway. It reduces proliferation and stemness in Wnt-dependent colorectal cancer cells in vitro and has demonstrated efficacy in suppressing HCT116 xenograft tumor growth in vivo.

Research Area

Signal Transduction, Stem Cell & Developmental Biology

Key Properties

• CAS Number: 1011440-46-2
• MW: 421.56
• Formula: C₂₄H₂₇N₃O₂S
• SMILES: O=C1CCCC1SC2=NN=C(N2C(C=3C=CC=CC3)C)COC4=CC=C(C=C4)CC
• Target: Wnt/beta-catenin

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

24242759