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GAT2711

SKU: orb3134307

Description

GAT2711 is a full agonist of α9nAChR, with an EC50 of 230 nM. It exhibits 340 times greater selectivity for α9 over α7nAChR. In THP-1 cells, GAT2711 inhibits ATP-induced IL-1β release. Additionally, GAT2711 retains full analgesic activity in α7nAChR knockout mice.

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Key Properties

FormulaC20H27IN4O
TargetAChR

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Protocol Information

GAT2711 (orb3134307)

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(Recommended: An additional animal making an allowance for loss during the experiment)

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