Gastric Inhibitory Peptide (22-51) (human) TFA

SKU: orb1980091

Description

GIP (22-51) is a 30-amino acid pro-atherogenic peptide found in human plasma. At 1 µM, it induces IκB-α degradation and NF-κB nuclear translocation in THP-1 macrophages and aortic endothelial cells, and exacerbates atherosclerotic lesions in ApoE-/- mice, making it a relevant tool for cardiovascular disease research.

Research Area

Immunology & Inflammation; Gastroenterology & Hepatology

Key Properties

• MW: 3181.60
• Formula: C₁₄₀H₂₂₆N₄₄O₄₁.XCF₃COOH
• SMILES: OC(C(F)(F)F)=O.O=C(O)CC[C@H](N[H])C(N[C@@H](CCCCN[H])C(N[C@@H](CCCCN[H])C(N[C@@H](CCC(O)=O)C(NCC(N[C@@H](CC1=CNC=N1)C(N[C@H](C(N[C@@H](CO)C(N[C@H](C(N[C@H](C(N2CCC[C@H]2C(N[C@@H](CO)C(N[C@H](C(N3CCC[C@H]3C(N[C@@H](C(C)C)C(NCC(N[C@@H](CO)C(N[C@@H](CC4=CNC=N4)C(N[C@H](C(N[C@@H](CCCCN[H])C(N[C@@H](C(C)C)C(N[C@@H](CO)C(N[C@@H](CO)C(N5CCC[C@H]5C(N[C@@H](CCC(N)=O)C(N6CCC[C@H]6C(N[C@@H](CCCNC(N)=N)C(NCC(N7CCC[C@H]7C(N[C@@H](CCCNC(N)=N)C(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)C)=O)=O)=O)=O)=O)=O)CC(C)C)=O)=O)=O)CC(C)C)=O)C)=O)=O)CC8=CC=CC=C8)=O)=O)=O)=O)=O)=O

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

170915834