Gastric Inhibitory Peptide 1 (3-42) (human) TFA

SKU: orb1980105

Description

GIP(3-42) is a DPP-4-generated GIP receptor antagonist. In ob/ob mice, it elevates blood glucose and reduces insulin, an effect replicated in vitro by inhibiting insulin secretion from BRIN-BD11 cells at 100 nM. This peptide is a valuable tool for studying incretin physiology and diabetes pathophysiology.

Research Area

Immunology & Inflammation; Gastroenterology & Hepatology

Key Properties

• MW: 4749.30
• Formula: C₂₁₄H₃₂₄N₅₈O₆₃S.XCF₃COOH
• SMILES: O=C(O)CC[C@H](N[H])C(NCC(N[C@]([C@H](O)C)([H])C(N[C@H](C(N[C@@](C(N[C@@H](CO)C(N[C@@H](CC(O)=O)C(N[C@@H](CC1=CC=C(O)C=C1)C(N[C@@H](CO)C(N[C@@](C(N[C@H](C(N[C@@H](CCSC)C(N[C@@H](CC(O)=O)C(N[C@@H](CCCCN[H])C(N[C@@](C(N[C@@H](CC2=CNC=N2)C(N[C@@H](CCC(N)=O)C(N[C@@H](CCC(N)=O)C(N[C@@H](CC(O)=O)C(N[C@H](C(N[C@@H](C(C)C)C(N[C@@H](CC(N)=O)C(N[C@@H](CC3=CNC4=C3C=CC=C4)C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CCC(N)=O)C(N[C@@H](CCCCN[H])C(NCC(N[C@@H](CCCCN[H])C(N[C@@H](CCCCN[H])C(N[C@@H](CC(N)=O)C(N[C@@H](CC(O)=O)C(N[C@@H](CC5=CNC6=C5C=CC=C6)C(N[C@@H](CCCCN[H])C(N[C@@H](CC7=CNC=N7)C(N[C@@H](CC(N)=O)C(N[C@@](C(N[C@]([C@H](O)C)([H])C(N[C@@H](CCC(N)=O)C(O)=O)=O)=O)([H])[C@@H](C)CC)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)C)=O)CC(C)C)=O)CC(C)C)=O)=O)=O)=O)CC8=CC=CC=C8)=O)=O)=O)=O)=O)([H])[C@@H](C)CC)=O)=O)=O)=O)C)=O)([H])[C@@H](C)CC)=O)=O)=O)=O)=O)([H])[C@@H](C)CC)=O)CC9=CC=CC=C9)=O)=O)=O.OC(C(F)(F)F)=O

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

170915401