Ganoderic acid H

SKU: orb1684591

Description

Ganoderic acid H

Research Area

Cell Biology, Molecular Biology, Signal Transduction

Key Properties

• CAS Number: 98665-19-1
• MW: 572.69
• Purity: 95.00% (May vary between batches)
• Formula: C₃₂H₄₄O₉
• SMILES: CC(CC(=O)CC(C)C(O)=O)C1CC(=O)C2(C)C3=C(C(=O)C(OC(C)=O)C12C)C1(C)CCC(O)C(C)(C)C1CC3=O
• Target: NF-κB|||DNA/RNA Synthesis|||CDK
• Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (5.76 mM);DMSO:80 mg/mL (139.69 mM)

Bioactivity

• In Vitro:
  In highly invasive human breast cancer cells, Ganoderic acid H suppressed growth (cell proliferation and colony formation) and invasive behavior (adhesion, migration and invasion) of MDA-MB-231 cells. Furthermore, the activity of Ganoderic acid H is linked to the hydroxylation in the positions 7 and 3 in its triterpene lanostane structure. Ganoderic acid H could be a promising natural agent for the therapy of invasive breast cancers.
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Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

CDK, DNASynthesis, DNA Synthesis, AP-1, Ganoderic acid H, inhibit, Inhibitor, NFκB, NF-κB, NFkB, NF-kB, RNA Synthesis, RNASynthesis

Compound Identifiers

PubChem CID

73657194