Gallopamil hydrochloride

SKU: orb1309645

Description

Gallopamil hydrochloride

Research Area

Metabolism Research, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 16662-46-7
• MW: 521.09
• Purity: 99.86%
• Formula: C₂₈H₄₁ClN₂O₅
• SMILES: CC(C)C(CCCN(C)CCc(cc1)cc(OC)c1OC)(c(cc1OC)cc(OC)c1OC)C#N.Cl
• Target: Calcium Channel
• Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (3.84 mM);DMSO:60 mg/mL (115.14 mM)

Bioactivity

• In Vivo:
  In male Wistar rats, Gallopamil hydrochloride (0.2 mg/kg; i.v. for 5 min) markedly reduces ventricular tachycardia and totally prevents fibrillation. Gallopamil hydrochloride significantly reduces systolic and diastolic blood pressure measured 5 min after injection without markedly influencing heart rate.
• In Vitro:
  Gallopamil hydrochloride inhibits acid secretion in a concentration-dependent manner with an IC50 of 10.9 μM.

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

CalciumChannel, Ca2+, Ca2+ channels, calcium, Calcium Channel, Ca channels, Ca(2+) receptor, antiarrhythmic, Methoxyverapamil, Methoxyverapamil hydrochloride, Methoxyverapamil Hydrochloride, inhibit, Inhibitor, Gallopamil, Gallopamil hydrochloride, Gallopamil Hydrochloride, phenylalkylamine, Verapamil, vasodilator

Compound Identifiers

PubChem CID

119442