Galarubicin hydrochloride

SKU: orb3174001

Description

Galarubicin hydrochloride (DA 125) is a novel anthracycline derivative with a strong affinity for DNA binding and topoisomerase II inhibition. It can induce apoptosis and exhibits cytotoxic effects through the JNK pathway. Galarubicin hydrochloride is useful for research in hepatocellular carcinoma.

Research Area

Cell Biology, Molecular Biology, Signal Transduction

Key Properties

• CAS Number: 140637-82-7
• MW: 670.04
• Formula: C₃₀H₃₃ClFNO₁₃
• SMILES: O([C@@H]1C2=C(C(O)=C3C(=C2O)C(=O)C=4C(C3=O)=CC=CC4OC)C[C@](C(COC(CCN)=O)=O)(O)C1)[C@H]5[C@H](F)[C@H](O)[C@H](O)[C@H](C)O5.Cl
• Target: Topoisomerase,DNA Alkylator/Crosslinker,Apoptosis,JNK

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

Topoisomerase,DNA Alkylator/Crosslinker,Apoptosis,JNK