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GAK inhibitor 2

SKU: orb1688333

Description

GAK inhibitor 2 (Compound 14g) is a potent and selective cyclin G-associated kinase (GAK) inhibitor (IC₅₀ = 24 nM). It demonstrates significant antiviral activity against dengue virus (DENV) in vitro (EC₅₀ = 1.049 µM), making it a valuable chemical probe for researching host-directed antiviral strategies and GAK biology.

Research Area

Infectious Disease & Virology, Pharmacology & Drug Discovery

Images & Validation

Key Properties

CAS Number2396706-31-1
MW385.48
FormulaC20H23N3O3S
SMILESC[C@@H]1CN(C2=C3C(=NS2)C=CC(=N3)C4=CC(OC)=C(OC)C=C4)C[C@H](C)O1
TargetOthers,Antibiotic,Anti-infection

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Key Properties

No computed properties available.

Protocol Information