G7-18NATE

SKU: orb2563761

Description

G7-18NATE is a peptide inhibitor of the Grb7-SH2 domain with micromolar binding affinity (K D = 18.1 µM). It is a research tool used in vitro to study mechanisms of cancer cell proliferation, motility, and invasion, and to investigate Grb7 signaling pathways in oncology.

Research Area

Cardiovascular Research, Signal Transduction

Key Properties

• Target: EGFR
• CAS Number: 936728-13-1
• MW: 1417.5
• Formula: C₆₇H₈₀N₁₄O₁₉S
• SMILES: C(C=1C=2C(NC1)=CC=CC2)[C@H]3C(=O)N[C@@H](CC4=CC=CC=C4)C(=O)N[C@@H](CCC(O)=O)C(=O)NCC(=O)N[C@@H](CC5=CC=C(O)C=C5)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@]([C@@H](C)O)(C(=O)N[C@@H](CC6=CC=CC=C6)C(=O)N7[C@](C(=O)N[C@H](C(N)=O)CSCC(=O)N3)(CCC7)[H])[H]

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

137655696