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G12Si-1

SKU: orb1686279

Description

G12Si-1 is a selective, covalent inhibitor of the K-Ras(G12S) oncoprotein. It effectively disrupts oncogenic signaling by binding the mutant serine residue and can impede nucleotide exchange processes. This inhibitor is a valuable tool for investigating K-Ras-driven cancers in both cellular and biochemical studies.

Research Area

Pharmacology & Drug Discovery, Signal Transduction

Images & Validation

Key Properties

MW534.05
FormulaC29H32ClN5O3
TargetRas,Others

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Protocol Information