G108

SKU: orb1739817

Description

G108 is a selective small molecule inhibitor of human cyclic GMP-AMP synthase (cGAS). It is a valuable research tool for investigating cGAS-mediated innate immune pathways in autoimmune and inflammatory diseases, applicable in both cellular and animal model studies.

Research Area

Immunology & Inflammation

Key Properties

• CAS Number: 2369750-66-1
• MW: 365.21
• Purity: 99.94% (May vary between batches)
• Formula: C₁₆H₁₄Cl₂N₄O₂
• SMILES: O=C(N1CC=2C=3C(=CC(Cl)=C(Cl)C3NC2CC1)C=4C=NNC4)CO
• Target: cGAS
• Solubility: H2O:120 mg/mL (328.58 mM)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

G108, G-108, G 108, cGAS, CNP 520, CNP-520, Umibecestat HCl, Umibecestat hydrochloride

Compound Identifiers

PubChem CID

138393371