Fusaproliferin

SKU: orb3024216

Description

Fusaproliferin is a diterpene mycotoxin identified in Fusarium solani. Fusaproliferin can reverse Lipopolysaccharides stimulation and the NF-κB and MAPKs signaling pathways, thus playing a role in anti-inflammatory processes. It has affinity for the TLR4 protein with a KD value of 28.6 μM. Fusaproliferin exhibits cytotoxicity against pancreatic cancer, showing rapid submicromolar IC50 effects.

Research Area

Cell Biology, Immunology & Inflammation, Metabolism Research, Signal Transduction

Key Properties

• CAS Number: 152469-17-5
• Target: Interleukin,IκB/IKK,NO Synthase,Reactive Oxygen Species,TNF,p38 MAPK,ERK,NF-κB

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

Interleukin,IκB/IKK,NO Synthase,Reactive Oxygen Species,TNF,p38 MAPK,ERK,NF-κB