FTO-IN-14

SKU: orb2944357

Description

FTO-IN-14 (Compound F97) is a potent FTO demethylase inhibitor (IC50 = 0.45 µM) that modulates ASB2, RARA, and MYC protein expression. It demonstrates in vitro antiproliferative and pro-apoptotic activity in AML cell lines and exhibits in vivo antitumor efficacy in mouse xenograft models, supporting its use in oncology and epigenetics research.

Research Area

Metabolism Research

Key Properties

• MW: 393.502
• Formula: C₂₂H₂₃N₃O₂S
• SMILES: CC(NN=C1C)=C1C2=CC(C3CC3)=C(NC4=C(C(O)=O)SC=C4)C(C5CC5)=C2
• Target: Apoptosis

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

176455394