FTI 277 TFA

SKU: orb1690061

Description

FTI 277 TFA is a potent farnesyltransferase (FTase) inhibitor (IC50 = 0.5 nM) that blocks Ras protein processing and MAPK signaling. It exhibits broad antiproliferative activity against various tumor cell lines, including human malignant gliomas, making it a valuable tool for investigating Ras-driven oncogenesis in both cellular and animal models.

Research Area

Cell Biology, Immunology & Inflammation, Metabolism Research, Signal Transduction

Key Properties

• CAS Number: 1217447-06-7
• MW: 561.64
• Formula: C₂₄H₃₀F₃N₃O₅S₂
• SMILES: OC(=O)C(F)(F)F.COC(=O)[C@H](CCSC)NC(=O)c1ccc(NC[C@@H](N)CS)cc1-c1ccccc1
• Target: Ras,Others,Transferase,Apoptosis

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

71311821