FPR2 agonist 5

SKU: orb3173553

Description

FPR2 agonist 5 is a selective agonist of formyl peptide receptor 2 (FPR2). It induces Ca2+ mobilization in HL60 cells transfected with FPR2, demonstrating an EC50 value of 1.2 μM, and causes FPR2 desensitization with an IC50 of 0.32 μM. Additionally, FPR2 agonist 5 exhibits neuroprotective effects by reducing LDH release, NO production, and the levels of IL-1β, IL-6, IL-33, and IL-10 in LPS-induced primary microglial cells from mice. It is utilized in research related to neuroinflammatory and inflammatory diseases.

Research Area

Immunology & Inflammation, Metabolism Research, Pharmacology & Drug Discovery

Key Properties

• Target: Interleukin,NO Synthase,Calcium Channel

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

Interleukin,NO Synthase,Calcium Channel