FPH1

SKU: orb1300708

Description

FPH1 (BRD-6125) is a small molecule that facilitates the proliferation of hepatocytes derived from induced pluripotent stem cells (iPSCs). It is a valuable research tool for liver disease modeling, drug toxicity screening, and studying hepatic development and regeneration in vitro.

Research Area

Metabolism Research

Key Properties

• CAS Number: 708219-39-0
• MW: 388.82
• Purity: 99.91% (May vary between batches)
• Formula: C₁₆H₁₅ClF₂N₂O₃S
• SMILES: Cc1ccc(Cl)cc1N(CC(=O)Nc1c(F)cccc1F)S(C)(=O)=O
• Target: Cytochromes P450,Others
• Solubility: Ethanol:< 1 mg/mL (insoluble or slightly soluble);DMSO:72 mg/mL (185.18 mM);10% DMSO+40% PEG300+5% Tween-80+45% Saline:3.3 mg/mL (8.49 mM);H2O:< 1 mg/mL (insoluble or slightly soluble)

Bioactivity

• In Vitro:
  FPH1 induces functional proliferation of hepatocytes in vitro, and causes more pronounced hepatocyte morphologies, including polygonal cell shapes, visible nuclei, and more noticeable bile cannaliculi between hepatocytes.

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

FPH 1, FPH1, FPH-1, Inhibitor, inhibit, BRD-6125, BRD6125, BRD 6125

Compound Identifiers

PubChem CID

2210370