Fosnetupitant chloride monohydrochloride

SKU: orb2278870

Description

Fosnetupitant chloride monohydrochloride is a methylene phosphate prodrug of the selective NK1 receptor antagonist netupitant, exhibiting high affinity (pKi 9.5) for the human NK1 receptor. It is utilized in research for investigating antiemetic mechanisms and pharmacokinetics in both in vitro and in vivo experimental models.

Research Area

Neuroscience, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 1643757-72-5
• MW: 761.52
• Formula: C₃₁H₃₇Cl₂F₆N₄O₅P
• SMILES: O=C(C(C)(C)C1=CC(C(F)(F)F)=CC(C(F)(F)F)=C1)N(C)C2=CN=C(N3CC[N+](COP(O)(O)=O)(CC3)C)C=C2C4=C(C)C=CC=C4.[Cl-].Cl
• Target: Neurokinin receptor

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

86764535