Forsythoside B

SKU: orb1221761

Description

Forsythoside B binds to LPS and reduces the biological activity of serum LPS, and inhibits NF-κB activation. Forsythoside B inhibits the inflammatory response and has antioxidant properties. Potent neuroprotective effects with a favorable therapeutic time-window, reduce of cerebral ischemia and reperfusion injury degree, attenuating blood-brain barrier (BBB) breakdown; Rescued cardiac function from I/R injury. Forsythoside B has antisepsis effect, is mediated by decreasing local and systemic levels of a wide spectrum of inflammatory mediators.

Key Properties

• CAS Number: 81525-13-5
• MW: 756.71
• Purity: >98% (HPLC)
• Formula: C₃₄H₄₄O₁₉
• SMILES: O1[C@H]([C@@H]([C@H]([C@@H]([C@H]1CO[C@@H]1OC[C@]([C@H]1O)(O)CO)OC(=O)/C=C/c1cc(c(cc1)O)O)O[C@@H]1O[C@H]([C@@H]([C@H]([C@H]1O)O)O)C)O)OCCc1cc(c(cc1)O)O
• Target: NF-κB
• Solubility: DMSO : 125 mg/mL 165.19 mM

Storage & Handling

• Storage: Storage temperature: -20°C. Stability: ≥ 2 years
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

NF-κB