Foretinib phosphate

• Catalog Number: orb1738293
• Category: Small Molecules
• Description: Foretinib phosphate
• CAS Number: 1226999-07-0
• Purity: 0.98
• MW: 828.65
• SMILES: OP(O)(O)=O.OP(O)(O)=O.COc1cc2c(Oc3ccc(NC(=O)C4(CC4)C(=O)Nc4ccc(F)cc4)cc3F)ccnc2cc1OCCCN1CCOCC1
• Formula: C₃₄H₄₀F₂N₄O₁₄P₂
• Biological Activity: Foretinib phosphate is an orally bioavailable small molecule with potential antineoplastic activity. MET/VEGFR2 inhibitor GSK1363089 binds to and selectively inhibits hepatocyte growth factor (HGF) receptor c-MET and vascular endothelial growth factor receptor 2 (VEGFR2), which may result in the inhibition of tumor angiogenesis, tumor cell proliferation and metastasis. The proto-oncogene c-MET has been found to be over-expressed in a variety of cancers.
• Note: For research use only
• Expiration Date: 12 months from date of receipt.