Folate-MS432

SKU: orb1942388

Description

Folate-MS432 is a folate receptor-targeted PROTAC that selectively induces degradation of MEK proteins in cancer cells. This bifunctional molecule is a research tool for studying targeted protein degradation in oncology, with applications in both in vitro and in vivo models of folate receptor-positive cancers.

Research Area

Pharmacology & Drug Discovery

Key Properties

• CAS Number: 2769735-56-8
• MW: 1679.65
• Formula: C₇₇H₉₄F₃IN₁₈O₁₂S
• SMILES: C([C@@H](NC(CCCCCCCCCCNCCCONC(=O)C1=C(NC2=C(F)C=C(I)C=C2)C(F)=C(F)C=C1)=O)C(C)(C)C)(=O)N3[C@H](C(N[C@@H](C)C4=CC=C(C=C4)C=5SC=NC5C)=O)C[C@@H](OC(CCCCN6C=C(CNC(CC[C@H](NC(=O)C7=CC=C(NCC=8N=C9C(NC8)=NC(N)=NC9=O)C=C7)C(O)=O)=O)N=N6)=O)C3
• Target: PROTACs

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

171361183