FNIII14

SKU: orb3142492

Description

FNIII14 is derived from the 14th type III-like (FN-III) repeat sequence of the fibronectin (FN) molecule. It inhibits cellular adhesion to the extracellular matrix (ECM) by inducing β1-integrin (β1integrin) to shift from an active to an inactive state, blocking integrin-mediated signaling. With its antifibrotic and anticancer properties, FNIII14 is useful for research in metabolic diseases, organ fibrosis, and malignancies.

Research Area

Signal Transduction

Key Properties

• Target: Integrin
• CAS Number: 206536-96-1
• MW: 2255.52
• Formula: C₁₀₃H₁₆₃N₂₁O₃₅
• SMILES: C([C@@H](NC([C@@H](NC(CNC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H]([C@@H](C)O)N)=O)CCC(O)=O)=O)C)=O)[C@@H](C)O)=O)[C@H](CC)C)=O)[C@@H](C)O)=O)=O)CC(C)C)=O)CCC(O)=O)(=O)N1[C@H](C(NCC(N[C@H](C(N[C@H](C(N[C@@H](CC2=CC=C(O)C=C2)C(N[C@H](C(N[C@H](C(N[C@@H](CC3=CC=C(O)C=C3)C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC(C)C)C(O)=O)=O)C)=O)[C@H](CC)C)=O)C(C)C)=O)=O)[C@H](CC)C)=O)[C@@H](C)O)=O)=O)CCC(O)=O)=O)[C@@H](C)O)=O)=O)CCC1

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

Integrin