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FMP

SKU: orb2944643

Description

FMP, a platinum(IV) complex, demonstrates potent antiproliferative activity against breast cancer cells. It induces DNA damage (γ-H2AX upregulation), oxidative stress (ROS increase), and activates both extrinsic and intrinsic apoptotic pathways, as evidenced by elevated p53, DR5, caspase-8, Cyt-c, and cleaved-PARP1. This mechanism supports its investigation in preclinical oncology research.

Research Area

Cell Biology, Epigenetics & Chromatin, Immunology & Inflammation, Metabolism Research, Molecular Biology, Protein Biochemistry, Signal Transduction

Images & Validation

Key Properties

MW640.33
FormulaC18H18Cl2N2O7Pt
TargetApoptosis,Caspase,PARP,MDM-2/p53,Reactive Oxygen Species,ROS,Bcl-2 Family

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Quality Guarantee

Quality Guarantee

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our Terms & Conditions and Buying Guide. Contact us at [email protected].

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FMP (orb2944643)

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