Fmoc-Gly-NH-CH2-O-Cyclopropane-CH2COOH

SKU: orb2564811

Description

This compound, Fmoc-Gly-NH-CH2-O-Cyclopropane-CH2COOH, is a key small-molecule intermediate for synthesizing cleavable ADC linkers. It is designed for coupling to payloads like Exatecan and subsequent conjugation to antibodies (e.g., hu2F7) for the development of targeted cancer therapeutics in preclinical research.

Key Properties

• CAS Number: 2414254-47-8
• MW: 424.45
• Formula: C₂₃H₂₄N₂O₆
• SMILES: C(OC(NCC(NCOC(C(O)=O)C1CC1)=O)=O)C2C=3C(C=4C2=CC=CC4)=CC=CC3
• Target: ADC Linker

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

155733577